Dear Tushar,
Key to helping prevent irrevocable vision loss from glaucoma is early detection combined with effective treatment. But to date, mechanisms to evaluate the progression of glaucoma have been limited.
Now investigators with the Catalyst for a Cure (CFC) Biomarker Initiative are on the verge of upending this barrier through the identification of new biological markers for glaucoma. Biomarkers can provide physicians with better tools to diagnose and manage glaucoma before vision is lost, as well as accelerate the pace of discovery toward better treatments and ultimately a cure for glaucoma.
Thanks to the CFC Biomarker Initiative, identification of molecular biomarkers for glaucoma has greatly accelerated. The CFC investigators have made extraordinary progress in speeding the progress of investigation, and they are now at a critical tipping point.
With the aid of the diagnostic tools they created, the researchers have identified biomarkers that may be among the earliest to show changes in glaucoma.
Functional tests for these new biomarkers have been validated in models of glaucoma and are now being tested in patients. "Our ability to bridge from laboratory studies to human studies, and now take that into the clinic, is what we set out to do six years ago," says CFC principal investigator Andrew Huberman, PhD.
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